
GutRx Calm+
Gut-brain support for a calmer mind and an easier mood.
- Magnesium, L-theanine, and saffron for calm
- Targets the gut-brain axis
- Supports mood and stress resilience
- Best taken in the afternoon or evening
Description
Advanced Gut-Brain Support for Calm Focus & Emotional Balance
GutRx Calm+ is a comprehensive gut-brain axis support formula designed to help promote mental calm, emotional balance, and digestive comfort—without sedation or stimulants.
By combining targeted minerals, calming amino acids, clinically studied botanicals, neuro-supportive lipids, prebiotics, and gut-brain probiotics, Calm+ supports both the mind and the microbiome, where much of the body’s stress signaling begins.
What Makes GutRx Calm+ Different?
✔ Multi-pathway gut-brain support
✔ Helps promote calm without drowsiness
✔ Supports emotional balance and stress response
✔ Includes prebiotics + probiotics for gut signaling
✔ Enteric-coated, delayed-release capsules
✔ Non-GMO | GMP-Certified | Third-Party Tested
How GutRx Calm+ Works
(Because calm doesn’t start in the head alone)
Over 90% of serotonin and many stress-related signals originate in the gut. Stress, poor diet, and inflammation can disrupt this communication, affecting mood, focus, and digestive comfort.
GutRx Calm+ works by supporting:
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Neurotransmitter balance
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Gut-brain signaling
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Inflammatory modulation
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Microbiome stability
The result is a more grounded, resilient sense of calm—built from the inside out.
Ingredient Breakdown & Functional Benefits
🧠 Mineral & Amino Acid Support
Magnesium (as Magnesium Bisglycinate) – 100 mg (24% DV)
Supports nervous system regulation and muscle relaxation; gentle and well-tolerated.
Zinc (as Zinc Carnosine) – 15 mg (136% DV)
Supports gut lining integrity and neurological signaling, helping maintain healthy gut-brain communication.
L-Theanine – 200 mg
An amino acid known to promote relaxed focus and calm alertness without sedation.
🌸 Botanical & Lipid Calm Support
Saffron Extract (Crocus sativus) – 15 mg
(Standardized to 2% safranal; equivalent to 30 mg dried stigma)
Traditionally used to support mood balance and emotional well-being.
Palmitoylethanolamide (PEA) – 300 mg
A naturally occurring fatty acid that supports the body’s response to stress and neuroinflammation.
🌱 Prebiotic Support for the Gut-Brain Axis
Galacto-oligosaccharides (GOS) – 500 mg
Derived enzymatically from lactose; supports beneficial gut bacteria linked to mood signaling.
Fructooligosaccharides (FOS) – 250 mg
Non-GMO beet-derived prebiotic fiber that nourishes microbiota involved in neurotransmitter production.
🦠 Gut-Brain Probiotic Blend – 12 Billion CFU
Bifidobacterium rhamnosus LRa66 – 4 Billion CFU
Associated with gut-brain signaling and stress resilience.
Lactobacillus plantarum Lp18 – 4 Billion CFU
Supports digestive balance and inflammatory modulation.
Lactobacillus fermentum NMCC-14 – 2 Billion CFU
Contributes to gut barrier health and immune balance.
Bifidobacterium longum BL11 – 2 Billion CFU
Linked to emotional balance and gut comfort.
Why Enteric-Coated & Delayed-Release?
Calm+ uses plant-based HPMC enteric coating to help protect sensitive ingredients through stomach acid, ensuring delivery where gut-brain signaling occurs.
Who GutRx Calm+ Is For
✔ Individuals dealing with daily stress or mental overload
✔ Those seeking calm without sedation
✔ People with stress-related digestive discomfort
✔ Anyone interested in gut-brain axis support
✔ Users wanting a science-driven calm formula
Suggested Use
Take 2 capsules daily, preferably with food.
For best results, use consistently.
Clean Label Promise
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60 Delayed-Release Vegetable Capsules (30 servings)
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Non-GMO
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GMP-Certified Facility
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Third-Party Tested (Eurofins)
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Free from major allergens
Other Ingredients:
Plant-based hydroxypropyl-methylcellulose (HPMC) enteric coating
GutRx Calm+
Calm the Gut. Steady the Mind. Support the Signal Between Them.
How to Use
Shipping and Returns
Orders ship within 1 business day. Free US shipping on orders over $75. Returns accepted within 90 days.
What It Does for Your Gut
Real outcomes, backed by clinically studied strains.
Less Bloating
Targeted strains help reduce occasional bloating and gas so you feel lighter after meals.
Better Regularity
Supports healthy, comfortable digestion and a more predictable routine.
Immune Support
About 70% of your immune system lives in your gut. Feed it well.
Inside Every Dose
Every strain is included at a clinically relevant amount, and we tell you exactly why it is there.
Strain Details
Lactobacillus rhamnosus LRa66
4 Billion CFUSupports the gut-brain axis and a balanced mood.
Lactobacillus plantarum Lp18
4 Billion CFUSupports gut barrier integrity.
Lactobacillus fermentum NMCC-14
2 Billion CFUSupports a balanced microbiome.
Bifidobacterium longum BL11
2 Billion CFUStudied for stress and mood support via the gut-brain axis.
Supplement Facts
| Serving Size: 2 capsules Servings Per Container: 30 |
% DV | |
|---|---|---|
| Magnesium (as Magnesium Bisglycinate) | 100 mg | 24% |
| Zinc (as Zinc Carnosine) | 15 mg | 136% |
| L-theanine | 200 mg | † |
| Saffron Extract (Crocus sativus, std to 2% safranal, equiv to 30 mg dried stigma) | 15 mg | † |
| Galacto-oligosaccharides (GOS) | 500 mg | † |
| Fructooligosaccharides (FOS) | 250 mg | † |
| Palmitoylethanolamide (PEA) | 300 mg | † |
| Lactobacillus rhamnosus LRa66 | 4 Billion CFU | † |
| Lactobacillus plantarum Lp18 | 4 Billion CFU | † |
| Lactobacillus fermentum NMCC-14 | 2 Billion CFU | † |
| Bifidobacterium longum BL11 | 2 Billion CFU | † |
† Daily Value (DV) not established. Other Ingredients: Plant-based Hydroxypropyl-methylcellulose (HPMC) enteric coating.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Calm+ works along the gut-brain axis with ingredients like saffron, L-theanine, and magnesium. For patients whose gut symptoms flare with stress, that connection matters.
Dr. Roshini Raj, MD
Board Certified Gastroenterologist, GutRx Medical Advisor
What to Expect
A healthy gut is built over weeks, not overnight. Here is a realistic timeline.
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Weeks 1 to 2
Settling In
Your microbiome starts adjusting. Mild changes in digestion are normal as new strains colonize.
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Weeks 3 to 4
Finding Rhythm
Many customers notice less bloating and a more regular routine.
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Week 8 and beyond
New Baseline
With daily use, digestive comfort and regularity become your new normal.
Real People,
Real Results
See how GutRx fits into real daily routines.

Daily Digestion

Helps digest processed foods

Gas and Bloat relief

"I cannot recommend this more"
Try It Risk Free for 90 Days
Give your gut a full 90 days. If you do not feel a difference, we will refund your order in full. No return shipping, no hoops.
Real Results from Real Customers
Frequently Asked Questions
When should I take it?
Take it daily, with or without food. Consistency matters more than timing.
Does it need refrigeration?
No. Our strains are shelf stable and protected until they reach your colon.
How do subscriptions work?
Choose your delivery frequency at checkout. You can pause, skip, or cancel anytime from your account.





