GutRx Leaky Gut (Intestinal Permeability) & Gut Lining Integrity Bundle

A complete repair stack for the intestinal barrier — fuel the gut lining, reinforce tight junctions, thicken the protective mucus layer, and rebuild the connective tissue underneath.

A healthy gut lining is a single-cell-thick barrier that decides what gets into your bloodstream and what stays out. When that barrier becomes too permeable — "leaky gut" — undigested particles and bacterial toxins can slip through, driving inflammation and endotoxemia. Repairing it takes more than one nutrient: you have to fuel the cells, reinforce the junctions between them, restore the protective mucus layer, and rebuild the structural tissue beneath.

The GutRx Leaky Gut & Gut Lining Repair Bundle brings together five formulas that each target a different layer of the gut barrier.

Fuel & tight junctions

• GutRx FIBER+ supplies the gut lining's core repair nutrients. L-Glutamine is the primary fuel source for enterocytes (the cells that line your intestine), zinc carnosine is well studied for supporting mucosal integrity, and PHGG feeds the bacteria that keep tight junctions intact — together helping restore barrier function from the inside.

Mucus layer & postbiotic reinforcement

• GutRx COMPLETE reinforces the barrier from multiple angles: tributyrin (a butyrate prodrug) feeds colonocytes and supports the gut lining, Akkermansia muciniphila helps thicken the protective mucus layer, and postbiotics (Lactobacillus ferment lysate, peptidoglycan, lipoteichoic acid) further support barrier resilience.
• GutRx BALANCE adds targeted mucus-layer support. Its Akkermansia muciniphila specifically promotes mucus layer thickness and barrier function, alongside next-gen strains that re-establish overall gut flora balance. Best taken before bed.

Structural rebuilding

• GutRx Collagen BT-3 provides Type III bovine collagen — a key structural protein of the intestinal lining and soft tissue — giving the gut's extracellular matrix the amino acid building blocks it needs to repair and stay resilient.
• GutRx Collagen MT-1 adds Type I marine collagen to support mucosal healing and the gut's connective tissue, complementing Type III for full-spectrum structural support.

Together they cover every layer of barrier repair: fuel the lining cells, reinforce the tight junctions and mucus layer, and rebuild the structural tissue underneath.

What you can expect

• Support for a stronger, less permeable intestinal barrier
• A thicker protective mucus layer and reinforced tight junctions
• Structural support for the gut lining's connective tissue
• Bonus skin, joint, and connective-tissue benefits from the collagens

Every GutRx formula is third-party lab tested with downloadable COAs, made in the USA, non-GMO, and free from major allergens — and backed by our 90-Day Gut Health Guarantee.